From the North Carolina Department of Health and Human Services 

We have received an influx of applications since the COVID-19 Vaccine Management System (CVMS) Provider Enrollment Portal opened to providers on January 11, 2021 and thank you for your enthusiasm around COVID-19 vaccine administration. Given the number of applicants, we want to provide insight into how providers are currently being approved for enrollment. 

Please understand that while qualified providers are welcome to enroll, applications will be reviewed in an order aligned with the prioritization phases, and the timeline for approval will vary. The table below highlights the six prioritization groups as well as target timing for enrollment decisions.

Provider Type 

Target Approval Timing 

(1) Hospitals, Health Systems, LHDs 

November / December 

(2) FQHCs, LTC Pharmacies, LHD Identified Partners, Correction Health, Mass Vaccinators   

December / January 

(3) Family Medicine/Internal Medicine, Medical Directors SNF, Occupational Health 

January / February 

(4) Retail Pharmacy, Pediatric Primary Care, Independent Practice Specialty 

February / March 

(5) Other Providers (e.g. Dental, Optometry) 

TBD pending executive authorization to administer COVID-19 vaccines 

(6) Other Entities (e.g. Labs, Colleges, Universities) 


We ask for your patience as we review the thousands of provider applications. Please also remember that provider enrollment approval does not guarantee vaccine allocation. We will update you as we receive more information on the timing and prioritization of enrollment applications.  

Thank you for your continued support,   
NC Immunization Branch  





NC Department of Health and Human Services

We are writing to inform you that starting today (1/11/21), North Carolina’s COVID-19 Vaccine Management System (CVMS) Provider Enrollment Portal is open.  Please share this message with any providers you are aware are eligible and interested in administering the COVID-19 vaccine.

Any provider enrolling through the portal will be reviewed and considered for approval by the NC Immunization Branch to administer the COVID-19 vaccine. Enrollment can be initiated here:

As a reminder, COVID-19 vaccine providers must be qualified under the CDC agreement to prescribe COVID-19 vaccines and authorized under the appropriate NC licensing authority. Enrolled COVID-19 vaccine providers must be credentialed/licensed in North Carolina. Please understand that while currently qualified providers are welcome to enroll, requests will be addressed in an order aligned with the prioritization phases and the timeline for approval will vary. The State will continuously reassess enrollment prioritization based on needs.

Please visit the North Carolina Immunization Branch COVID-19 training website for Provider Enrollment Portal training content: The available modules are captured in the screenshot below.  

CVMS Provider Enrollment  
Additional trainings related to CVMS can also be found on Please note, any trainings you elect to review at this time are subject to be refreshed by the time you become an approved provider. You may need to revisit trainings depending on approval timelines.

Thank you for your continued support,

NC Immunization Branch